Malignant transformation of Lung Bulla

Neethu K Kumar, Sreejith V S, Sunny George, Anandan P T, James P T


Cases of malignant transformation in bullous lung disease are not infrequent, and most of these cancers turn out to be non small cell lung cancer. However, they are often difficult to diagnose because of their uncertain appearance. Here we report a case of bullous lung disease, now presenting with an air – fluid level, in which a diagnosis of malignancy was made by ultrasound, guided fine needle aspiration cytology. Hence this possibility has to be kept in mind when a known case of bullous lung disease presents with worsening symptoms or new radiological shadows which is often treated as secondary infection of a preexisting bulla.

Key words: Malignant transformation, Bullous Lung Disease, ultrasound guided fine needle aspiration


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Shinji Hirai, Yoshiharu Hamanaka, Norimasa Mitsui et al. Primary Lung Cancer Arising from the wall of a Giant Bulla. Case Report.Ann Thorac Cardiovasc SurgVol.11,No.2(2005)

Walid Abu, Vincent Echave, Macro Sirois et al, Incidental caecinoma in bullous emphysema. Case Report, J can chir Vol 52 2009

Masanori Kanedaa,, Tomohito Tarukawaa, Fumiaki Watanabea et al.Clinical features of primary lung cancer adjoining pulmonary bulla. Interactive CardioVascular and Thoracic Surgery 10 (2010) 940–944

Ahmet Başoğlu, Ayşen Taslak Şengül, Yasemin Bilgin. Synchronous lung adenocarcinoma associated with bullous lung disease. Türk Göğüs Kalp Damar Cer Derg 2009;17(1):51-53

Diacon AH, Schuurmans MM, Theron J, Schubert PT, Wright CA, Bolliger CT. Safety and yield of ultrasound-assisted transthoracic biopsy performed by pulmonologists.Respiration 2004; 71: 519-22.


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